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glutathione biosynthesis akt AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells

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glutathione biosynthesis akt AKT activation because of PTEN loss upregulates xCT via GSK3/NRF2, leading  to inhibition of ferroptosis in PTEN-mutant tumor cells
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